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Leveraging the regional perspective to facilitate the personalisation of health - towards smart health

Leveraging the regional perspective to facilitate the personalisation of health - towards smart health

Personalised Medicine (PM) is strongly technological driven and will induce a transformation of how health and well-being are approached, and medicine is being implemented. The convergence of knowledge on what determines health and disease or how the process of ageing is determined, with digital technologies and access to data opens a huge potential to develop new applications to improve general health and to secure the sustainability of our healthcare systems.

PM developments are impacting virtually all domains of modern medicine. Approaches building on the latest insights on the biological functioning of single cells are currently among the most promising areas. One of the key factors for successful implementation of PM is the availability to standardised, accessible, processed data, which also enables the re-use of publicly available data for exploring multidisciplinary research goals. Next to access to and gathering of data, the availability of a highly qualified biomedical and healthcare workforce to generate, analyse and process PM data to translate data into new products and applications is an essential requirement.

Vision of the pilot

The pilot aims at realising the potential of personalised medicine as part of the S3 platforms on Industrial Modernisation. This pilot will bring the agenda to implement personalised medicine to the next level, while transforming the connected European industrial value chains. The partner regions already established solid ecosystems combining biomedical, technological and data driven expertise. By bringing these ecosystems together, a higher added value will be reached and boost the implementation of personalised medicine; it will realise an innovative approach for health and care in Europe.

State of play of the PILOT

The pilot is active in the four phases of the methodology. After the initial scoping, the network has been established as a learning- and co-creation community, which exchanges knowledge on a regular basis by organising tailormade workshops and connecting the different regional stakeholders in events or digital seminars. This connection is based on the quadruple helix; involving stakeholders from research & innovation, businesses and field labs, regional and local governments, hospitals and healthcare centres as well as clients and citizens. Demo-cases will be brought forth by partner regions. After an initial presentation of the demo-case proposal complementary expertise will be assessed. A GAP- and SWOT-analysis will highlight the knowledge that needs to be added to the project and identify the pilot partners best suited to take up the role in question. The demonstration phase will entail the operation of large scale interregional pilots based on the four objectives. This implementation in the regions will enable the last phase of commercialisation of new products and services by the private sector.

PLANNED DEMO CASES

1. Personal Data Management Platform

The Personal data management platform project brings together three regions and their health ecosystem to provide a personal digital safe and the control over it to each individual citizen. The collective of this data organized in a citizen-centric governance model provides currently non-existing possibilities for innovation and an ethically correct market place for personalized products and services.

2. P4 medicine-Citizen lab

In the aim of establishing a European wide living lab for PM measures in different (chronic) diseases a first consortium has been established on Diabetes Type II. A broad programme on prevention including learning communities and social innovation clusters will be developed based on mission programmes in the field of cardiovascular diseases, kidney diseases and arthrosis.

3. Mobile Health (R)Evolution - Chronic Diseases Control

The project aim is to generate value to users and society by offering elderly chronic disease patients continuous, personalised health professionals’ support through mobile health management for better self-management of chronic diseases and quality of life. The project addresses social challenges (communication, inclusion of patients in the healthcare process, patient motivation) & biomedical aspects (pharmaceutical care). The empowerment of patients will be achieved with knowledge and motivation as well as ICT tools to take over disease management and ultimately improve quality of life.

COORDINATORS OF THE PILOT REGIONS PARTICIPATING IN THE PILOT
Flanders (BE)
South Netherlands (NL)
East Netherlands (NL)
Slovenia, North Ostrobothnia (FI), Southwest Finland (FI), Piemonte (IT), Emilia-Romagna (IT), Extremadura (ES), Nord-Est (RO), Capital region of Denmark Flanders (BE)
OTHER STAKEHOLDERS PARTICIPATING

Academia/research centres: IMEC, VITO, Flanders Make, VIB, University Twente, Radboud UMC, Radboud University, Wageningen University & Research, Maastricht University, MUMC+, Chemelot InSciTe, AMIBM Industry sector: DSP Valley, FlandersBio, MedTech Flanders, Blue Health Innovation Center
Governments/public institutions: Flemish government, Flanders’ Care, Province Gelderland, Province Overijssel, Province of Limburg, NV Industriebank LIOF
End-users' representatives from different countries: UZ Leuven, Health House, VERSO, Cluster Twente, Brightlands Maastricht Health Campus, Brightlands Greenport Venlo, Brightlands Smart Services Campus

CONTACTS
Kathleen D'Hondt
, Kathleen.dhondt [at] vlaanderen.be
Karolien de Bruine, Karolien.deBruine [at] oostnl.nl  
Dirk Plees, d.plees [at] prvlimburg.nl